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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396850Generated: October 29, 2026

3-(4-Bromophenyl)4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol → 4-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methylisoxazole

https://huagongshe.com/reaction/396850

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Bromophenyl)4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazololHCID 22723950—
Reactant4-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazololHCID 54348463—
Product4-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methylisoxazoleHCID 54286531—

Reaction Steps

The title compound was prepared according to the procedure of step 2 in the Example 168 using 4-(4-bromophenyl)-3-(4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol, instead of 3-(4-bromophenyl)-4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608095B2
Source datasetuspto-grants-2003_08
ORD IDord-08bffd908f8647bcb4f73342c56cdb23
Source noteuspto-grants-2003_08