Acetic Anhydride → HCID 22672666, compound

HRID 396972Notes

Reaction equation

[CH2:1]([CH:5]([C:7]1[N:8]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:9]2[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[N:12]=[CH:11][C:10]=2[N:19]=1)[OH:6])[CH2:2][CH2:3][CH3:4].[C:24](OC(=O)C)(=[O:26])[CH3:25]>>[C:24]([O:6][CH:5]([C:7]1[N:8]([CH2:20][CH:21]([CH3:22])[CH3:23])[C:9]2[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[N:12]=[CH:11][C:10]=2[N:19]=1)[CH2:1][CH2:2][CH2:3][CH3:4])(=[O:26])[CH3:25]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 22672651HCID 22672651, compound

Product 1

HCID 22672666HCID 22672666, compound

Procedure

Using the general method of Example 46, α-butyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol (11.6 g; 37 mmol, Example 56) was reacted with acetic anhydride to provide the desired product.

Sources & evidence

ORD record: ord-4c0937eca5ab4ac187d30ab10c305c22
Source dataset: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06608201B2

Reaction notes

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