Methyl iodide → HCID 22672662, compound

HRID 396974Notes

Reaction equation

HRID 396974 reaction equation
[CH3:1][CH:2]([C:4]1[N:5]([CH2:17][CH:18]([CH3:20])[CH3:19])[C:6]2[C:15]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=[CH:8][C:7]=2[N:16]=1)[OH:3].[CH3:21]I>>[CH3:21][O:3][CH:2]([C:4]1[N:5]([CH2:17][CH:18]([CH3:20])[CH3:19])[C:6]2[C:15]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=[CH:8][C:7]=2[N:16]=1)[CH3:1]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 15224403alpha-Methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol

Product 1

HCID 22672662HCID 22672662, compound

Procedure

Using the general method of Example 49, α-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol (3 g; 11 mmol, Example 63) was reacted with methyl iodide to provide 2.4 g of the desired product. The structure was confirmed by nuclear magnetic resonance spectroscopy.

Sources & evidence

ORD record
ord-9cba4ff8339a4bef822c351cb5ae69d3
Source dataset
uspto-grants-2003_08
Patent number
US06608201B2

Reaction notes

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