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HRID 396981作成日：2026年10月25日

Glycolic Acid → 2-(Hydroxymethyl)-Alpha,Alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

https://huagongshe.com/reaction/396981

反応式

関与物質

役割名称HCID仕込み量
反応物Glycolic AcidHCID 757—
反応物1-((3-Aminoquinolin-4-yl)amino)-2-methylpropan-2-olHCID 14986941—
生成物2-(Hydroxymethyl)-Alpha,Alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanolHCID 22672658—

反応手順

Using the general method of Example 24, 3-amino-4-(2-hydroxy-2-methylpropylamino)quinoline (45 g, 0.19 mol) was reacted with glycolic acid to provide 35.7 g of the desired product as a tan solid. The structure was confirmed by nuclear magnetic resonance spectroscopy.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06608201B2
出典データセットuspto-grants-2003_08
ORD IDord-1e02acccf44943218c679b2c49b52e4d
出典メモuspto-grants-2003_08