HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dihydroxybenzaldehyde → 4-Benzyloxy-2-hydroxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dihydroxybenzaldehyde | HCID 7213 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-Benzyloxy-2-hydroxybenzaldehyde | HCID 561235 | — |
Reaction Steps
13.8 g (0.1 mol) 2,4-dihydroxybenzaldehyde are dissolved in 150 ml acetone, 17.1 g (0.1 mol) benzylbromide and 13.8 g (0.1 mol) potassium carbonate are added, and the mixture is stirred at room temperature for 3 d. After filtration, the solvent is removed in vacuo and the residual crude product further purified by column chromatography on silica gel using dichloromethane as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610687B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-18617ac054bb42f287216936d8a4275d |
| Source note | uspto-grants-2003_08 |