N-bromobutanimide → HCID 57543474, compound

HRID 397328Notes

Reaction equation

HRID 397328 reaction equation
[CH3:1][O:2][C:3](=[O:13])[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([F:11])[C:6]=1[I:12].[Br:14]N1C(=O)CCC1=O>C(#N)C>[CH3:1][O:2][C:3](=[O:13])[NH:4][C:5]1[CH:10]=[CH:9][C:8]([Br:14])=[C:7]([F:11])[C:6]=1[I:12]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 69364178HCID 69364178, compound

Product 1

HCID 57543474HCID 57543474, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

(4-Bromo-3-fluoro-2-iodo-phenyl)-carbamic acid methyl ester was prepared from (3-fluoro-2-iodo-phenyl)-carbamic acid methyl ester by reaction with N-bromosuccinimide in acetonitrile in the presence of trifluoromethansulfonic acidm.p.:162-164° C.

Workup

  1. custom162-164° C.

Sources & evidence

ORD record
ord-e166a4017e544a8890bb6e9271c3f3dd
Source dataset
uspto-grants-2003_08
Patent number
US06610685B2

Reaction notes

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