HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycol monoacetate → Methyl 3-(2-Acetoxyethoxy)-2-hydroxy-3,3-diphenylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycol monoacetate | HCID 10960 | — |
| Reactant | Methyl 3,3-diphenyloxirane-2-carboxylate | HCID 10587027 | — |
| Catalyst | Boron trifluoride etherate | HCID 8000 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Methyl 3-(2-Acetoxyethoxy)-2-hydroxy-3,3-diphenylpropionate | HCID 15379666 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
7.95 g (31.3 mmol) of methyl 3,3-diphenyl-2,3-epoxypropionate were dissolved in 20 ml of diethyl ether under N2 and cooled to 0° C., and 5.87 ml (31.3 mmol) of 2-hydroxyethyl acetate (50% strength) and 3 drops of BF3.Et2O were added. After removal of the ice bath, the mixture was stirred at RT for 2 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610691B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-85f0a3e4a5b440e2a7a90efbfafe2bdb |
| Source note | uspto-grants-2003_08 |