HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 5-(4-Morpholin-4-yl-6-oxo-6,7-dihydro-pyrrolo[2,3-D]pyrimidin-5-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid (2-Morpholin-4-yl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 5-(4-chloro-6-oxo-6,7-dihydro-pyrrolo[2,3-d]pyrimidin-5-ylidenemethyl)-1H-pyrrole-2-carboxylic acid (2-morpholin4-yl-ethyl)-amide | HCID 86586502 | — |
| Product | 5-(4-Morpholin-4-yl-6-oxo-6,7-dihydro-pyrrolo[2,3-D]pyrimidin-5-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid (2-Morpholin-4-yl-ethyl)-amide | HCID 85331771 | 35% |
Reaction Steps
The title compound (35% yield) was prepared from 5-(4-chloro-6-oxo-6,7-dihydro-pyrrolo[2,3-d]pyrimidin-5-ylidenemethyl)-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide and morpholine according to the procedure described for Example 14. MS-EI 453 [MZ+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610688B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-c3c6f5efee68411887bbdf372e4b197b |
| Source note | uspto-grants-2003_08 |