7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one → 6-Methoxy-1,2-dihydronaphthalene

HRID 397620Notes

Reaction equation

HRID 397620 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][CH2:9][CH:10]2O)=[CH:5][CH:4]=1.COC1C=C2C(CCCC2=O)=CC=1>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6](=[CH:5][CH:4]=1)[CH2:7][CH2:8][CH:9]=[CH:10]2

Participants

3

Reactant 2

HCID 812767-Methoxy-1,2,3,4-tetrahydronaphthalen-1-oneHCID 122431977-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol

Product 1

HCID 5947756-Methoxy-1,2-dihydronaphthaleneYield 96%

Procedure

6-Methoxy-1,2-dihydronaphthalene was synthesized analogously to Example 5b from 7-methoxy-1,2,3,4-tetrahydro-1-naphthalenol to give 4.4 g of product brown yellow oil (96% yield from 7-methoxy-1,2,3,4-tetrahydro-1-naphthalenone).

Sources & evidence

ORD record
ord-bc05bab43e104b64b7435bcfac4f1580
Source dataset
uspto-grants-2003_08
Patent number
US06610714B2

Reaction notes

Loading…