Benzaldehyde → HCID 23000721, compound

Participants

Reaction Steps

The title compound was prepared by a similar method to Example 13 from 2-(3-[1-(1H-benzo[d]imidazol-2-ylsulfonyl)-2-piperidyl]-1,2,4-oxadiazol-5-yl)ethylamine [see Example 27] and benzaldehyde. The crude product was purified by column chromatography on silica gel eluting with a solvent gradient of 99:1 changing to 98:2, by volume, dichloromethane:methanol to afford N-(2-(3-[1-(1H-benzo[d]imidazol-2-ylsulfonyl)-2-piperidyl]-1,2,4-oxadiazol-5-yl)ethyl)-benzylamine.

Provenance & Evidence