2-((1-((Benzyloxy)carbonyl)piperidin-4-YL)oxy)acetic acid → tert-butyl (2S)-2-[(Z)-N'-[2-(1-phenylmethoxycarbonylpiperidin-4-yl)oxyacetyl]oxycarbamimidoyl]piperidine-1-carboxylate

Participants

Reaction Steps

The title compound was prepared by a similar method to Preparation 5 from tert-butyl (Z)-(2S)-2-[amino(hydroxyimino)methyl]-1-piperidinecarboxylate [see Preparation 4] and 2-(1-[(benzyloxy)carbonyl]-4-piperidyloxy)acetic acid [see Preparation 92] to afford tert-butyl (Z)(2S)-2-[amino([2-(1-[(benzyloxy)carbonyl]-4 piperidyloxy)acetyl]oxyimino)methyl]-1-piperidinecarboxylate as a brown oil.

Provenance & Evidence