HRID397701

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23000701

未命名化合物

$结构：N/C(=N\O)[C@@H]1CCCCN1S(=O)(=O)CC1CCCCC1$

HCID59085897

未命名化合物

PRODUCTS

生成物

$结构：N/C(=N\OC(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)o1)[C@@H]1CCCCN1S(=O)(=O)CC1CCCCC1$

HCID59085909

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a similar method to Preparation 5 from (Z)-(2S)-1-[(cyclohexylmethyl)sulfonyl]-N′2-hydroxy-2-piperidinecarboximidamide [see Preparation 28] and 5-[(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)methyl]-2-furoic acid (see Preparation 98], to afford (Z)-(2S)-1-[(cyclohexylmethyl)sulfonyl]-N′2-[(5-[(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)methyl]-2-furylcarbonyl)oxy]-2-piperidinecarboximidamide as a yellow oil.

WORKUP

后处理

customPreparation 98],

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3f143839cf044ab98abd08d740ed41a3
来源数据集: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06610707B1
来源说明: uspto-grants-2003_08

反应 SMILES

[CH:1]1([CH2:7][S:8]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][C@H:12]2/[C:17](=[N:19]/[OH:20])/[NH2:18])(=[O:10])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[O:21]=[C:22]1[C:30]2[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=2)[C:24](=[O:31])[N:23]1[CH2:32][C:33]1[O:37][C:36]([C:38](O)=[O:39])=[CH:35][CH:34]=1>>[CH:1]1([CH2:7][S:8]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][C@H:12]2/[C:17](=[N:19]/[O:20][C:38]([C:36]2[O:37][C:33]([CH2:32][N:23]3[C:24](=[O:31])[C:25]4[C:30](=[CH:29][CH:28]=[CH:27][CH:26]=4)[C:22]3=[O:21])=[CH:34][CH:35]=2)=[O:39])/[NH2:18])(=[O:9])=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1