HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylene Glycol Monoethyl Ether → Carbazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| Reactant | 1,2,3,4-Tetrahydrocarbazole-4-carboxamide | HCID 22738726 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Carbazole-4-carboxamide | HCID 22741084 | — |
Reaction Steps
A 1,2,3,4-tetrahydrocarbazole-4-carboxamide or 4-carboxhydrazide (13) is dehydrogenated by refluxing in a solvent such as carbitol in the presence of Pd/C to produce the carbazole-4-carboxamide. Alternately, treatment of (13) with DDQ in an appropriate solvent such as dioxane yields carbozole (14).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610728B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-d758e5a7a8d04027b705df0f6362e8d1 |
| Source note | uspto-grants-2003_08 |