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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 397878Generated: October 25, 2026

3-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridine → 3-(3-Chloro-4-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine hydrochloride

https://huagongshe.com/reaction/397878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridineHCID 23444965—
Reactant2-(3-Chloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 23445107—
Product3-(3-Chloro-4-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine hydrochlorideHCID 23445103—

Reaction Steps

The title compound, MS: m/e=298.3 (M+H+) was obtained as a beige solid (78% yield) by the reaction of 3-bromo-5-(2-methyl-imidazol-1-yl-methyl)-pyridine with 2-(3-chloro-4-methyl-phenyl)-4,4,5,5-tetramethyl [1,3,2]-dioxaborolane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06610723B2
Source datasetuspto-grants-2003_08
ORD IDord-becdd11eb89a4865b553e1896a7cba81
Source noteuspto-grants-2003_08