Aluminium lithium hydride → HCID 23445017, compound

HRID 397920Notes

Reaction equation

HRID 397920 reaction equation
C[O:2][C:3]([C:5]1[N:6]=[CH:7][N:8]([C:10]2[CH:19]=[CH:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH:11]=2)[CH:9]=1)=O.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH:11]1[C:12]2[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:18]=[CH:19][C:10]=1[N:8]1[CH:9]=[C:5]([CH2:3][OH:2])[N:6]=[CH:7]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 69039389HCID 69039389, compound

Product 1

HCID 23445017HCID 23445017, compound

Procedure

Following the general method described in example 298) 1-naphthalen-2-yl-1H-imidazole-4-carboxylic acid methyl ester was reacted with lithium aluminum hydride followed by hydrolytic workup and chromatography. The title compound was obtained as a light brown gum. MS: m/e=225 (M+).

Sources & evidence

ORD record
ord-b7279a8743db41b6a75d6821575d8a88
Source dataset
uspto-grants-2003_08
Patent number
US06610723B2

Reaction notes

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