HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → Paeonol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 2',4'-Dihydroxyacetophenone | HCID 6990 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Paeonol | HCID 11092 | — |
Reaction Steps
2,4-Dihydroxyacetophenone was alkylated with bromoethane in acetone in the presence of potassium carbonate to obtain 2-hydroxy-4-methoxyacetophenone. Using this compound and 2-methoxy-benzoic acid as starting materials, the syntheses according to Examples 1a, b, c, and d yielded the compound (m.p.: 153-154.5° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610738B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-e7c351b4c9ad408cbfec23b35eb29bab |
| Source note | uspto-grants-2003_08 |