HCID 69872808, compound → HCID 22633508, compound

HRID 398182Notes

Reaction equation

HRID 398182 reaction equation
C([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH:36]=[CH:37][CH2:38][CH3:39])=[C:13]([CH:35]=1)[O:14][CH2:15][CH2:16][C:17]1[N:18]=[C:19]([C:23]2[CH:28]=[CH:27][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:25][CH:24]=2)[O:20][C:21]=1[CH3:22])C1C=CC=CC=1.[H][H]>C(O)C.[Pd]>[CH2:36]([C:12]1[CH:11]=[CH:10][C:9]([OH:8])=[CH:35][C:13]=1[O:14][CH2:15][CH2:16][C:17]1[N:18]=[C:19]([C:23]2[CH:24]=[CH:25][C:26]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:27][CH:28]=2)[O:20][C:21]=1[CH3:22])[CH2:37][CH2:38][CH3:39]

Participants

5

Reactant 2

HCID 69872808HCID 69872808, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22633508HCID 22633508, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 4-[2-(5-Benzyloxy-2-but-1-enylphenoxy)ethyl]-5-methyl-2-biphenyl-4-yl-oxazole (0.34 mmol) in ethanol (10 mL) was treated with 5% Pd/C (30 mg) under a balloon containing hydrogen at ambient temperature for 24 h. The mixture was filtered and concentrated in vacuo to give a white solid.

Workup

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated in vacuo
  3. customto give a white solid

Sources & evidence

ORD record
ord-972b55af7cb043ac89bd7a81cf7e07d4
Source dataset
uspto-grants-2003_08
Patent number
US06610696B2

Reaction notes

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