HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Benzenesulfonamide, N-methoxy-N-methyl-2-nitro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | Methanamine, N-methoxy-, hydrochloride (1:1) | HCID 81138 | — |
| Product | Benzenesulfonamide, N-methoxy-N-methyl-2-nitro- | HCID 23002393 | 1,793.6% |
Reaction Steps
2-Nitrobenzenesulfonyl chloride (5 g, 22.5 mmol) was allowed to react with N-methyl-N-methoxyamine hydrochloride (2.42 g, 22.5×1.2 mmol) in the presence of triethylamine (5.47 g, 22.5×2.4 mmol) to obtain 5.3 g (percent yield: 95.3%) of N-methyl-N-methoxy-2-nitrophenylsulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610853B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-0709710751af4cc183167212002dc1f7 |
| Source note | uspto-grants-2003_08 |