反应详情

温度

60 °C

To a suspension of 3-chloro-4-oxo-2,3,4,5-tetrahydro-1H- naphtho-[2,1-b]azepine (16.6 g, 67.6 mmol) in DMSO (80 ml) was added sodium azide (8.8 g, 135 mmol) and the suspension was heated at 60° C. for 5 h. The hot reaction mixture was poured into water (1 L). The precipitate was isolated by filtration and washed with water. After drying in vacuo 16.3 g of 3-azido-4-oxo-2,3,4,5-tetrahydro-1H-naphtho[2,1-b]azepine was obtained.

1. customThe precipitate was isolated by filtration
2. washwashed with water
3. dry with materialAfter drying in vacuo 16.3 g of 3-azido-4-oxo-2,3,4,5-tetrahydro-1H-naphtho[2,1-b]azepine
4. customwas obtained