HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium → (+/-)-3-Butyl-3-ethyl-2,3-dihydro-1,4-benzothiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium | HCID 5462222 | — |
| Reactant | (+/-)-3-Butyl-3-ethyl-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 18968854 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | (+/-)-3-Butyl-3-ethyl-2,3-dihydro-1,4-benzothiazepine | HCID 18968787 | 99.1% |
Reaction Steps
To a solution of the product from step (b) (6.0 g) in tert-butyl alcohol (180 ml) was added a solution of potassium permangante (5.7 g) in water (90 ml). The mixture was heated to reflux for 10 minutes, cooled to room temperature, and filtered through celite. Solvent was evaporated to provide the title compound (5.9 g) as a colorless oil. 1H NMR consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817652 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-b138a27a123e467da2a8f5b77082f856 |
| Source note | uspto-grants-1998_10 |