HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Nitrofuroyl chloride → 5-(N-[5-nitro-2-furoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Nitrofuroyl chloride | HCID 90711 | — |
| Reactant | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| Product | 5-(N-[5-nitro-2-furoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 19601525 | 64% |
Reaction Steps
Beginning with 0.10 gm (0.044 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.0093 mL (0.053 mMol) 5-nitro-2-furoyl chloride, 0.010 gm (64%) of the title compound were prepared essentially by the procedure described in Example 7.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817671 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-d3b4d79e0048490c87ff3f4c0b0bf559 |
| Source note | uspto-grants-1998_10 |