HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Bromothiophene-2-carbonyl chloride → 5-(N-[3-bromo-2-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Bromothiophene-2-carbonyl chloride | HCID 2797569 | — |
| Edukt | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| Produkt | 5-(N-[3-bromo-2-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 19601495 | 49,2% |
Reaktionsschritte
Beginning with 0.37 gm (1.6 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.45 gm (2.0 mMol) 3-bromo-2-thiophenecarbonyl chloride, 0.33 gm (49%) of the title compound were prepared essentially by the procedure described in Example 8.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05817671 |
| Quelldatensatz | uspto-grants-1998_10 |
| ORD ID | ord-208a4281493940138fb230a027161f1b |
| Quellennotiz | uspto-grants-1998_10 |