Pyridine-4-carbonyl chloride → HCID 19601506, compound

HRID 398926Notes

Reaction equation

HRID 398926 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14](C(OC(C)(C)C)=O)[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[N:24]1[CH:29]=[CH:28][C:27]([C:30](Cl)=[O:31])=[CH:26][CH:25]=1>>[N:24]1[CH:29]=[CH:28][C:27]([C:30]([NH:1][C:2]2[N:7]=[C:6]3[C:8]([CH:11]4[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]4)=[CH:9][NH:10][C:5]3=[CH:4][CH:3]=2)=[O:31])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 417436Pyridine-4-carbonyl chlorideHCID 117268345-Amino-3-(1-tert-butoxycarbonylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

Product 1

HCID 19601506HCID 19601506, compound

Procedure

Beginning with 0.015 gm (0.047 mMol) 5-amino-3-(1-tert-butoxycarbonylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.011 gm (0.062 mMol) 4-pyridinecarbonyl chloride, the title compound was prepared.

Sources & evidence

ORD record
ord-b97721a055184335a8a40ffdee5fc5ca
Source dataset
uspto-grants-1998_10
Patent number
US05817671

Reaction notes

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