2-Thiophenecarbonyl chloride → HCID 19601487, compound

HRID 398934Notes

Reaction equation

HRID 398934 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[S:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[C:24](Cl)=[O:25]>>[S:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[C:24]([NH:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1)=[O:25]

Participants

3

Reactant 2

HCID 789282-Thiophenecarbonyl chlorideHCID 117706865-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

Product 1

HCID 19601487HCID 19601487, compound

Procedure

Beginning with 0.015 gm (0.061 mMol) 5-amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.009 mL (0.080 mMol) 2-thiophenecarbonyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

Sources & evidence

ORD record
ord-6da9ad79216c4b50b9735a78617011e5
Source dataset
uspto-grants-1998_10
Patent number
US05817671

Reaction notes

Loading…