HCID 9903877, compound → HCID 10583903, compound

Participants

Reaction Steps

A mixture of 4-(2-benzylaminoethoxy)-1,3-dihydro-indol-2-one (1.93 g, 6.84 mmol) in absolute ethanol (50 mL) containing 10% palladium on carbon (400 mg) was shaken in a Parr hydrogenator for 4 days at room temperature. The catalyst was filtered and washed with methanol. The solvent was removed under vacuum to afford a light tan solid (1.15 g, 87.5%): mp 146°-148° C.; MS EI m/e 192 (M+): HRMS for C10 H12N2O2 calc 192.089878, found 192.0845365.

Provenance & Evidence