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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 399013Generated: October 30, 2026

Isoindoline → HCID 10638841, compound

https://huagongshe.com/reaction/399013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoindolineHCID 422478—
ReactantHCID 10704607HCID 10704607—
ProductHCID 10638841HCID 1063884175%

Reaction Steps

4-(2-Chloroethoxy)-7-fluoro-1,3-dihydro-indol-2-one was reacted with isoindoline in the same manner described for intermediate 16 to afford the title compound in 75% yield as a thick oil. The fumarate salt was prepared in ethanol: mp 210°-212° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05817690
Source datasetuspto-grants-1998_10
ORD IDord-252cb9b7741d44db84ddf1af7599a548
Source noteuspto-grants-1998_10