HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Xylyl chloride → 4-{2-[Bis-(3-methyl-benzyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Xylyl chloride | HCID 12102 | — |
| Reactant | HCID 10583903 | HCID 10583903 | — |
| Product | 4-{2-[Bis-(3-methyl-benzyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one | HCID 18969578 | 34% |
Reaction Steps
Utilizing 4-(2-amino-ethoxy)-1,3-dihydro-indol-2-one prepared in example 2 and reacting with 3-methylbenzyl chloride in the same manner as described for intermediate 15 above to afford the title compound as a crystalline solid in 34% yield, mp 162-164.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817690 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-1841fb1b9ba44c01b64ebcd5a35312b8 |
| Source note | uspto-grants-1998_10 |