HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorostyrene → (E)-1-(Methylthio)-4-[2-(3,5-difluorophenyl)ethenyl]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorostyrene | HCID 67883 | — |
| Reactant | Benzene, 1-methyl-4-(methylthio)- | HCID 69334 | — |
| Reactant | 1-Bromo-3,5-difluorobenzene | HCID 136313 | — |
| Solvent | Toluene hexane | HCID 21889329 | — |
| Product | (E)-1-(Methylthio)-4-[2-(3,5-difluorophenyl)ethenyl]benzene | HCID 18969709 | — |
Reaction Steps
Following the procedure describe in Method 3, but substituting 4-methylthiostyrene (from method 4, step 1) and 1-bromo-3,5-difluorobenzene for 4-fluorostyrene and 4-methylthioanisole, the title product was obtained after flash chromatography (silica gel; toluene/hexane (50:50)) as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817700 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-5cc8cf23531a49a48f92d6d1d00ca578 |
| Source note | uspto-grants-1998_10 |