Ethanol → HCID 18665754, compound

Participants

Reaction Conditions

Reaction Steps

2-(2-pyridyl)-2-phenyl oxirane (prepared following the procedure of Example 11, Step F) (0.106 g, 0.537 mmol) and S-(-)-ethyl nipecotate (0.093 g, 0.591 mmol) in EtOH (0.90 mL) were heated at 50° C. in a sealed tube with stirring for 24 hr. The reaction mixture was dissolved in EtOAc, washed with brine, dried (Na2SO4), filtered, and concentrated to dryness to give the title compound.

Provenance & Evidence