HCID 18665753, compound → HCID 18665735, compound

Participants

Reaction Steps

Ethyl 1-(2,2-Diphenylethyl)-3(S)-piperidine carboxylate (4.90 g, 0.014 mol) dissolved in dry ether (40 mL) was added to a suspension of lithium aluminum hydride (1.93 g, 0.051 mol) in dry ether (40 mL). The solution was refluxed until the starting material was consumed and then was quenched with saturated potassium sodium tartrate solution (100 mL) and stirred for 2 hr. The layers were separated and the aqueous layer extracted with ether (2×). The combined organic extracts were dried (MgSO4) and concentrated to yield the title compound without further purification.

Provenance & Evidence