Iodine → 1-[2-Oxo-2-(pyridin-2-yl)ethyl]pyridin-1-ium iodide

HRID 399146Notes

Reaction equation

HRID 399146 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[I:10]I>N1C=CC=CC=1>[I-:10].[N:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[C:1](=[O:3])[CH2:2][N+:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:4]=1

Participants

4

Reactant 2

HCID 807IodineHCID 142862-Acetylpyridine

Product 1

HCID 2134991-[2-Oxo-2-(pyridin-2-yl)ethyl]pyridin-1-ium iodide

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a stirred solution of 2-acetylpyridine (0.5 mole) in 600 mL pyridine is added iodine (127 g; 0.5 mole). The mixture is heated on a steam bath for 45 minutes, and the product crystallizes on cooling. The solid is filtered and the crystalline cake is rinsed twice with methylene chloride.

Workup

  1. temperatureThe mixture is heated on a steam bath for 45 minutes
  2. customthe product crystallizes
  3. temperatureon cooling
  4. filtrationThe solid is filtered
  5. washthe crystalline cake is rinsed twice with methylene chloride

Sources & evidence

ORD record
ord-1371ba484fc04f45a008e4c8e1246945
Source dataset
uspto-grants-1998_10
Patent number
US05817774

Reaction notes

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