HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl (RS)-I-(4methoxyphenyl)-3-phenylindene-2-carboxylate → Ethyl(1RS,2SR,3SR)-1-(4-Methoxyphenyl)-3-phenylindane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl (RS)-I-(4methoxyphenyl)-3-phenylindene-2-carboxylate | HCID 18969659 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl(1RS,2SR,3SR)-1-(4-Methoxyphenyl)-3-phenylindane-2-carboxylate | HCID 67643697 | — |
Reaction Steps
To a solution of ethyl(RS)-1-(4-methoxyphenyl)-3-phenylindene-2-carboxylate (5.75 g, 15 mmol) in EtOAc (150 ml) was added 5% palladium on activated carbon (600 mg). The resulting suspension was stirred under an atmosphere of H2 for 1 d, then was filtered through a pad of Celite. The filtrate was concentrated under reduced pressure to afford the title compound, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817693 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-2d64aff7473644cba00098b03448a31d |
| Source note | uspto-grants-1998_10 |