HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 44211033, compound → HCID 44211034, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 44211033 | HCID 44211033 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 44211034 | HCID 44211034 | 84.4% |
Reaction Steps
To a solution of (1RS,2SR,3 SR)-3-[2-[(E)-2-carboxy-ethen-1-yl]-4-methoxyphenyl]-1-(3,4-methylenedioxy-phenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid (43 mg, 0.08 mmol) in ethanol (5 mL) was added 10% palladium on activated carbon (40 mg). The resulting suspension was stirred overnight under an atmosphere of hydrogen then filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford the title compound (35 mg, 82%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817693 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-b5ed67280c9745ce8b4b531da8cc8563 |
| Source note | uspto-grants-1998_10 |