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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 399276Generated: October 26, 2026

2-((5-Methoxy-1H-indol-6-yl)oxy)-N,N-dimethylethan-1-amine → 1-(4'-Acetyl-3'-methylbiphenyl-4-carbonyl)-6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole

https://huagongshe.com/reaction/399276

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-((5-Methoxy-1H-indol-6-yl)oxy)-N,N-dimethylethan-1-amineHCID 10537659—
Reactant4'-Acetyl-3'-methylbiphenyl-4-carboxylic acidHCID 18970493—
Product1-(4'-Acetyl-3'-methylbiphenyl-4-carbonyl)-6-(2-dimethylaminoethoxy)-5-methoxy-1H-indoleHCID 18970489—

Reaction Steps

The title compound was prepared from 4'-acetyl-3'-methylbiphenyl-4-carboxylic acid (D21) and 6-(2-dimethylaminoethoxy)-5-methoxy-1H-indole (D13) using a similar procedure to Example 4 as an off-white solid mp 125°-127° C. (36%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05817833
Source datasetuspto-grants-1998_10
ORD IDord-d0c3a23c900647568b2db0dfb1fc4fdc
Source noteuspto-grants-1998_10