3-Bromo-2,5-bis(2,2,3,3,4,4,4-heptafluoro-1-trimethylsilyloxybutyl)pyrrole → 2,5-Bis(2',2',3',3',4',4',4'-heptafluoro-1'-trimethylsiloxybutyl)-3-trifluoromethylpyrrole
Reaction equation
[Cl-].[F:2][C:3]([Zn+])([F:5])[F:4].Br[C:8]1[CH:12]=[C:11]([CH:13]([O:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[C:14]([F:23])([F:22])[C:15]([F:21])([F:20])[C:16]([F:19])([F:18])[F:17])[NH:10][C:9]=1[CH:29]([O:40][Si:41]([CH3:44])([CH3:43])[CH3:42])[C:30]([F:39])([F:38])[C:31]([F:37])([F:36])[C:32]([F:35])([F:34])[F:33]>>[F:39][C:30]([F:38])([C:31]([F:36])([F:37])[C:32]([F:33])([F:34])[F:35])[CH:29]([C:9]1[NH:10][C:11]([CH:13]([O:24][Si:25]([CH3:28])([CH3:27])[CH3:26])[C:14]([F:22])([F:23])[C:15]([F:20])([F:21])[C:16]([F:17])([F:18])[F:19])=[CH:12][C:8]=1[C:3]([F:5])([F:4])[F:2])[O:40][Si:41]([CH3:42])([CH3:43])[CH3:44]Participants
3
Procedure
Trifluoromethylzinc chloride is reacted with 3-bromo-2,5-bis(2,2,3,3,4,4,4-heptafluoro-1-trimethylsilyloxybutyl)pyrrole utilizing reaction and purification conditions described in Example 22.
Sources & evidence
- ORD record
- ord-575141ba5b6149ae835c2a0450a47180
- Source dataset
- uspto-grants-1998_10
- Patent number
- US05817830
Reaction notes
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