HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18967564, compound → HCID 18967554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18967564 | HCID 18967564 | — |
| Reactant | 4-Chloro-6,7-dimethoxyquinazoline hydrochloride | HCID 22022161 | — |
| Product | HCID 18967554 | HCID 18967554 | 12% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 1-(4-amino-2-chlorophenyl)-1-(4-pyridyl)methanol was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 4-{3-chloro-4-[1-hydroxy-1-(4-pyridyl)methyl]anilino}-6,7-dimethoxyquinazoline dihydrochloride salt in 12% yield;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821246 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-1ab1becde0db495ba322eb4cd4e99e6d |
| Source note | uspto-grants-1998_10 |