2-Chloro-1-fluoro-4-nitrobenzene → HCID 885050, compound

HRID 399462Notes

Reaction equation

HRID 399462 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1F.[CH3:12][N:13]1[CH:17]=[CH:16][N:15]=[C:14]1[SH:18]>>[CH3:12][N:13]1[CH:17]=[CH:16][N:15]=[C:14]1[S:18][C:7]1[CH:6]=[CH:5][C:4]([N+:9]([O-:11])=[O:10])=[CH:3][C:2]=1[Cl:1]

Participants

3

Reactant 2

HCID 676882-Chloro-1-fluoro-4-nitrobenzeneHCID 178480602HCID 178480602, compound

Product 1

HCID 885050HCID 885050, compoundYield 87%

Procedure

Using an analogous procedure to that described in the first paragraph of the portion of Example 8 which is concerned with the preparation of starting materials, 3-chloro-4-fluoronitrobenzene was reacted with 1-methyl-2-imidazolethiol to give 2-chloro-4-nitrophenyl 1-methylimidazol-2-yl sulphide in 87% yield.

Sources & evidence

ORD record
ord-33a9eccd35c34e738252210e31779b77
Source dataset
uspto-grants-1998_10
Patent number
US05821246

Reaction notes

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