HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-(4-Aminophenyl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Propenoic acid, 3-(4-nitrophenyl)- | HCID 70156 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(4-Aminophenyl)propionic acid | HCID 75451 | — |
Reaction Steps
15 g of palladium on carbon (10% and 30 ml of water are added to a mixture of 155 g of 4-nitrocinnamic acid in 1 l of methanol, and hydrogenation is carried out at room temperature under 3 bar until no further hydrogen is taken up, after about 2 hours. After filtration and evaporation of the solvent in a rotary evaporator, residual water is removed by twice adding 300 ml portions of toluene and distilling off the solvent in a rotary evaporator.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05821240 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-080107e432b24871a28213b866e90934 |
| Source note | uspto-grants-1998_10 |