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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 399572Generated: November 2, 2026

Triethylamine → HCID 18946143, compound

https://huagongshe.com/reaction/399572

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant1-MethylpiperazineHCID 53167—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
ReactantHCID 178525760HCID 178525760—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 18946143HCID 18946143—

Reaction Steps

Prepared from 4-[(3-chloro-4-fluorop henyl)amino]-6-[trans-4-carboxycyclohexylamino]pyrimido[5,4-d]pyrimidine by reaction with O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, triethylamine and 1-methylpiperazine. Melting point: 194°-197° C.; Rf : 0.45 (alumina; methylene chloride/methanol=10:0.3)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05821240
Source datasetuspto-grants-1998_10
ORD IDord-a1e0b4beaaee4cc2ac19da1a870abdb1
Source noteuspto-grants-1998_10