Thiourea → 4-(2,4-dimethyl-5-pyridyl)-5-methyl-2-[N-(dicyclopropylmethyl)-N-propylamino]thiazole

HRID 399636Notes

Reaction equation

HRID 399636 reaction equation
Br[CH:2]([CH3:13])[C:3]([C:5]1[C:6]([CH3:12])=[CH:7][C:8]([CH3:11])=[N:9][CH:10]=1)=O.[CH:14]1([CH:17]([CH:25]2[CH2:27][CH2:26]2)[N:18]([CH2:22][CH2:23][CH3:24])[C:19]([NH2:21])=[S:20])[CH2:16][CH2:15]1.NC(N)=S>>[CH3:11][C:8]1[CH:7]=[C:6]([CH3:12])[C:5]([C:3]2[N:21]=[C:19]([N:18]([CH:17]([CH:25]3[CH2:27][CH2:26]3)[CH:14]3[CH2:15][CH2:16]3)[CH2:22][CH2:23][CH3:24])[S:20][C:2]=2[CH3:13])=[CH:10][N:9]=1

Participants

4

Reactant 3

HCID 2723790ThioureaHCID 18967796N-(dicyclopropylmethyl)-N-propylthiourea2×HCID 189678272-Bromo-1-(2,4-dimethyl-5-pyridyl)-1-propanone

Product 1

HCID 152916204-(2,4-dimethyl-5-pyridyl)-5-methyl-2-[N-(dicyclopropylmethyl)-N-propylamino]thiazole

Procedure

This compound was prepared according to the process described in Example 1, Step A, using 2-bromo-1-(2,4-dimethyl-5-pyridyl)-1-propanone (Coapound 27) as the ketone and N-(dicyclopropylmethyl)-N-propylthiourea (Compound 66) as the thiourea.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-2cd83dc92a034445b79533d9f4446067
Source dataset
uspto-grants-1998_10
Patent number
US05821255

Reaction notes

Loading…