Water → HCID 88257354, compound

HRID 399720Notes

Reaction equation

HRID 399720 reaction equation
[C:1]([P:7](=[O:10])([O-:9])[O-:8])([P:3](=[O:6])([O-:5])[O-:4])=[CH2:2].[Na+:11].[Na+].[Na+].[Na+].[S:15]1C=C[CH:17]=[C:16]1CC(O)=O.[OH2:24]>>[Na+:11].[Na+:11].[C:16]([S:15][CH2:2][CH:1]([P:7](=[O:9])([O-:8])[O-:10])[P:3](=[O:5])([OH:4])[OH:6])(=[O:24])[CH3:17]

Participants

4

Reactant 3

HCID 962WaterHCID 159702-Thiopheneacetic acidHCID 462028Tetrasodium ethene-1,1-diylbis(phosphonate)

Product 1

HCID 88257354HCID 88257354, compound

Procedure

Tetrasodium ethenylidenebis(phosphonate) (2.76 g, 10 mmol) [prepared as described in R. L. Carroll, U.S. Pat. No. 3,686,290 (1972) and in R. L. Carroll and M. M. Crutchfield, Canadian Patent 811,736 (1969)] and thiolacetic acid (3.81 g, 50 mmol) are dissolved in water (20 ml) and stirred at room temperature under an atmosphere of nitrogen for 20 hours. The reaction mixture is then concentrated under reduced pressure and further dried under vacuum overnight. The solid product is triturated in warm ethanol, cooled and filtered while washing with diethyl ether to yield pure product as a pale yellow solid.

Workup

  1. concentrationThe reaction mixture is then concentrated under reduced pressure
  2. customfurther dried under vacuum overnight
  3. customThe solid product is triturated in warm ethanol
  4. temperaturecooled
  5. filtrationfiltered
  6. washwhile washing with diethyl ether
  7. customto yield pure product as a pale yellow solid

Sources & evidence

ORD record
ord-d27d7ebb018845a3b3fcfd5eb68faf79
Source dataset
uspto-grants-1998_10
Patent number
US05824661

Reaction notes

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