Triethylamine → HCID 18944991, compound

Participants

Reaction Steps

0.2 g (0.33 mmol) N-(dimethyloxophosphinyl-methyl)-N-{3-methyl-5-[2-(2,3,5,6-tetrachloropyridin-4-ylamino)-ethoxy]-phenyl}-benzenesulfonamide in 10 ml methanol was hydrogenated in the presence of 0.28 ml triethylamine and 0.1 g 10% palladium on carbon at room temperature and normal pressure. After 18 hours it was filtered, the residue was dissolved in 3 ml ethanol, 30 ml ether was added, it was filtered, washed with ether and 0.12 g (77%) of the title compound of Fp. 228°-232° C. was obtained.

Provenance & Evidence