Methyl 3-(3-nitrophenyl)benzoate → (1,1'-Biphenyl)-3-carboxylic acid, 3'-amino-, methyl ester

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Reaction Steps

10% Palladium on carbon (0.4 g) was added to a solution of methyl 3-(3-nitrophenyl)benzoate (2.0 g) in methanol (30 ml) and the mixture was subjected to catalytic hydrogenation at ambient temperature under atmospheric pressure. After one hour, the catalyst was removed by filtration and the filtrate was evaporated in vacuo. The residue was crystallized from diethyl ether to afford methyl 3-(3-aminophenyl)benzoate (1.45 g).

Provenance & Evidence