反应详情

A solution of fumaric acid (0.46 g) in methanol (10 ml) was added to a solution of 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine (1.0 g) in methanol (10 ml) and the whole was stirred for 1 hour at ambient temperature. The isolated precipitate was collected by filtration and the precipitate was recrystallized from methanol-water to give 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine fumarate (1.03 g).

1. filtrationThe isolated precipitate was collected by filtration
2. customthe precipitate was recrystallized from methanol-water