HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorambucil → Indole-3-Acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorambucil | HCID 2708 | — |
| Reactant | 1H-Indole-3-propanoic acid | HCID 3744 | — |
| Reactant | Indole-3-Butyric Acid | HCID 8617 | — |
| Reactant | 5-Methoxyindoleacetic acid | HCID 18986 | — |
| Reactant | Flavone-8-Acetic Acid | HCID 55748 | — |
| Reactant | Benzo-1,3-dioxole-5-acetic acid | HCID 76115 | — |
| Reactant | 2-Methyl-1H-indole-3-acetic acid | HCID 589107 | — |
| Reactant | 3,4-Methylenedioxycinnamic acid | HCID 643181 | — |
| Reactant | 2-Indolylacetic acid | HCID 4371752 | — |
| Product | Indole-3-Acetic Acid | HCID 802 | — |
Reaction Steps
2-indolylacetic acid; (N-methyl)-2- or -3-indolylacetic acid; 3-(3-indolyl)propionic acid; 3- or 2-indolylacrylic acid (also (N-methyl)); (2-methyl-3-indolyl)acetic acid, 3,4-(methylenedioxy)phenylacetic acid; 3,4-(methylenedioxy)cinnamic acid; indole-3-butyric acid; (5-methoxyindol-3-yl)acetic acid; naphthyl-1- or -2-acetic acid; flavone-8-acetic acid; 5,6-dimethylxanthone-4-acetic acid (L. L. Thomsen et al.: Cancer Chemother, Pharmacol. 31, 151ff. (1992) demonstrate that the corticoid 21-carboxylic esters prepared from this could also have an antitumorigenic effect, likewise the abovementioned chlorambucil).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05824670 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-f17162eee9fd4fa2a1cf4cb44ea995ed |
| Source note | uspto-grants-1998_10 |