Water → HCID 53726946, compound

Participants

Reaction Steps

A solution of the compound obtained in Example 5 (1.68 g, 5.08 mmol), acetic anhydride (30 ml) and 4-dimethylaminopyridine (DMAP, 60 mg) in pyridine (60 ml) was stirred at room temperature for 4 days. The reaction mixture was poured into water and extracted with ethyl acetate. The organic layer was washed with brine and dried over magnesium sulfate. The solvent was distilled off under reduced pressure and the residue was purified by column chromatography on silica gel (hexane:ethyl acetate=3:1) to give the title compound (1.65 g, 78%) as a white solid.

Provenance & Evidence