4-Phenylpiperidine-4-carboxamide monohydrochloride → HCID 54367670, compound

Participants

Reaction Steps

Prepare by the method of example 27.3.1 using 2-[3-(3,4-dichloro-phenyl)-1-(3-isopropoxy-phenacyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate (0.24 g, 0.5 mmol) and 4-phenyl-piperidine-4-carboxylic acid amide hydrochloride (0.24 g, 0.98 mmol). Chromatograph on silica gel to give the title compound: Rf =0.45 (silica gel, 6% methanol/dichloromethane).

Provenance & Evidence