HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Ethoxy-3,5-dimethoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 4-ethoxy-3,5-dimethoxybenzoate | HCID 13652164 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Ethoxy-3,5-dimethoxybenzoic acid | HCID 13642510 | — |
Reaction Steps
Combine methyl 3,5-dimethoxy-4-ethoxy-benzoate (2.13 g, 9,421 mmol) and methanol (30 mL). Add a 1M aqueous solution of sodium hydroxide (50 mL, 50 mmol). After 1 hour, acidify the reaction mixture using a 1M aqueous hydrochloric acid solution, extract with ethyl acetate. Dry the organic layer over MgSO4, filtered and evaporated in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05824690 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-aaaa39689fe84263b7a454a741ea3aed |
| Source note | uspto-grants-1998_10 |