HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine-4-carboxamide monohydrochloride → (R)-1-[2-[3-(3,4-dichloro-phenyl)-1-benzoyl-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine-4-carboxamide monohydrochloride | HCID 3017129 | — |
| Reactant | (S)-2-[3-(3,4-dichloro-phenyl)-1-(benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate | HCID 86753254 | — |
| Product | (R)-1-[2-[3-(3,4-dichloro-phenyl)-1-benzoyl-pyrrolidin-3-yl]-ethyl]-4-phenyl-piperidine-4-carboxylic acid amide | HCID 86753253 | — |
Reaction Steps
Prepare by the method of Example 1.6 using (S)-2-[3-(3,4-dichloro-phenyl)-1-(benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate and 4-phenyl-piperidine-4-carboxylic acid amide hydrochloride to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05824690 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-41a234d414fd420f872c84a6b8c4c712 |
| Source note | uspto-grants-1998_10 |