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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400142Generated: October 26, 2026

Hexanoic Acid → HCID 53677539, compound

https://huagongshe.com/reaction/400142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexanoic AcidHCID 8892—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 53677539HCID 5367753931.2%

Reaction Steps

A procedure similar to that described in Example 3, above, was followed, but using 1.0 g (1.8 mmol) of (4R,6R)-6-{2-[(1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above] and 423 mg (3.6 mmol) of hexanoic acid, to provide 364 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05827855
Source datasetuspto-grants-1998_10
ORD IDord-fa902037a8124293842d1a74f1bf4013
Source noteuspto-grants-1998_10